Through the long distance warp called the "Exodus Project", Worns, Ryer and the other crew members of "Watchers Nest" manage to escape from the Earth. Misaki, who was attending the final battle with "Ghoul" at that time, isn't present there and before her eyes, the earth changes and gets enclosed by a time barrier. Ryer and the others search for a way to escape from this space time maze, but the earth changes to various forms. Innumerable "Nows" appear due to varying time axes. And also Misaki, who should have disappeared because of the Exodus Project incident, still afortiori. Before Ryer and the others, different forms of Misaki appear. The Misaki from training school, the Misaki from her childhood days. Are these reflections caused by the conflicts that exist inside Misaki? She awakens a second time and when she derives the response, that history is leading into a completely differnet direction now. Will Misaki, Ryer and the others be able to find a real happy end?! (Source: AnimeNfo)

Four years into the future, the world has lost its balance... 10 thousand metres of vast woodland is gone, preventing humans to live and leaving a desert to spread endlessly. And so, they head into the world of Meshichi, to live together with the Anbots. As if guided by fate, Sanzou and Gokyuu meet. Traveling together, Sanzou - a young man shrouded in mystery, Gokyuu - the strongest and worst Anbot around, Tongoh - an Anbot fond of drinking, Jou - someone who is great with machines, Suuji - a female Anbot thief, and last but not least, Mioto. And so, their journey begins to the boundless East, to the land where the sun was born! (Source: AnimeNfo)

"Mushi": the most basic forms of life in the world. They exist without any goals or purposes aside from simply "being." They are beyond the shackles of the words "good" and "evil." Mushi can exist in countless forms and are capable of mimicking things from the natural world such as plants, diseases, and even phenomena like rainbows. This is, however, just a vague definition of these entities that inhabit the vibrant world of Mushishi, as to even call them a form of life would be an oversimplification. Detailed information on Mushi is scarce because the majority of humans are unaware of their existence. So what are Mushi and why do they exist? This is the question that a "Mushishi," Ginko, ponders constantly. Mushishi are those who research Mushi in hopes of understanding their place in the world's hierarchy of life. Ginko chases rumors of occurrences that could be tied to Mushi, all for the sake of finding an answer. It could, after all, lead to the meaning of life itself. [Written by MAL Rewrite]

Perceived as strange and feared by man, over time the misshapen ones came to be known as Mushi. Although they harbor no ill intentions towards humans, many suffer from the side effects of their existence and strange nature; exploiting the Mushi without understanding them, even unintentionally, can lead to disaster and strife for any involved. Mushishi Zoku Shou continues the story of Mushishi Ginko on his journey to help the visible world to coexist with the Mushi. During his travels, Ginko discovers various gifted individuals—those cursed by circumstance and those maintaining a fragile symbiosis with the Mushi—inevitably confronting the question of whether humanity, talented and tortured alike, can manage the responsibility of the unseen. Moreover, as a Mushishi, Ginko must learn more about these strange beings and decide if he has the right to interfere with the complex relationships between Mushi and mankind. [Written by MAL Rewrite]