Panty and Stocking Anarchy, the angel twin sisters, have even more ghosts to exorcize in Daten City, thanks to the failed opening of the Hell Gate. They must continue their ghost hunt alongside their longtime rivals, the sisters Scanty and Kneesocks Demon, who must earn Hell Coins to return to Hell. On top of that, the Demon sisters are staying at the church with Garterbelt, the priest in charge of the Anarchy sisters. These two polar opposite duos will have to set aside their differences if they wish to collect enough Heaven and Hell Coins to complete their mission and return to their respective realms.

Toto has been dreaming about adventuring with other people for as long as he can remember. Despite his hero title, he still remains without allies due to his timid personality. Therefore, when three women: Ciel, Anemone, and Goa suddenly request to join him, Toto is overjoyed. Unbeknownst to him, they are all assassins assigned to eliminate him! While Toto resolves to protect his would-be killers, the women fight over who can finish off the hero. As Toto remains oblivious of his new party members' true intentions and finds himself passing out every time he gets flustered, the four of them embark on their peculiar adventure into the greater world.

High school first year Yuu Yuutani has always been a good girl, following the rules, helping out around her house, and generally going through life unnoticed. From afar, she reveres her upperclassman and the school's Public Decency Officer, Atori Mizutori, and desperately wants her attention. When she realizes that the best way to get Atori to notice her is to be a delinquent, she begins to dress differently: she dyes parts of her hair a bright red, wears clips on her ears to resemble piercings, and attaches jumbo erasers to her shoes to give them thicker soles. Despite Yuu's best efforts and even with the advice of her "natural born delinquent" friend Suzu Suzukaze, all of her plans to be a bad girl go awry. Still, Yuu manages to befriend Atori and pledges to spend as much time as possible together, not knowing there are others vying for Atori's attention. In the process, Yuu has also gained the attention of the school's self-proclaimed idol, Rura Ruriha, filling her once-invisible life with more attention than she may be able to handle.

After Marin Kitagawa introduced Wakana Gojou to the world of cosplay, he has been creating her outfits with ease. Even so, he still has a lot to learn, and every new lesson seems to strengthen his love for sewing and for the hina dolls his grandfather taught him to make. Meanwhile, Kitagawa finds it harder and harder to hide her feelings for Gojou. Friends and strangers alike constantly mistake them for a couple, much to Gojou's embarrassment. After all, in his eyes, their worlds are far too different for anyone to think they could be romantically linked. However, as Gojou spends more time with Kitagawa and realizes that his passions are not ridiculed by other people, a relationship between the two no longer seems so far-fetched.