Yurume, an 18-year-old "ronin" and recent high school graduate, has high hopes of being accepted and attending Tokyo University. She moves into an apartment complex, the Maison du Wish, located on the outskirts of Tokyo where other ronins living there are studying for upcoming college acceptance exams.

The continuation of Yurumates 3D right after the first season.

Once a hot springs inn, now a boarding house with extraordinarily cheap rent, Yuragi-sou is virtually uninhabited save for a few peculiar residents. As rumor has it, it is haunted by a vile ghost which scares away all potential tenants. Therefore, it is the perfect refuge for Fuyuzora Kogarashi—a broke, homeless psychic seeking an affordable roof to stay under and ghosts to exorcise. Kogarashi prepares for a face-off against the ghost, only to find out it is not as malicious as the rumors made it out to be. Instead, it is the ghost of a beautiful, silver-haired girl whose only recollection of her life before death is her name: Yuuna. Even more baffling is that the other tenants of Yuragi-sou not only are able to see Yuuna as well, but each has their own supernatural ability. Amidst the chaos caused by his quirky fellow residents, Kogarashi attempts to uncover the regret that keeps Yuuna anchored to the world of the living, lest she become an evil spirit sentenced to spend her afterlife in hell. [Written by MAL Rewrite]

Taking place after the events of the fourth film, the series centers on 11 yr old Keisuke Amano, Natsume's younger brother (both of whom are the children of Keita Amano and Fumika Kodama of the original Youkai Watch anime) who doesn't believe in any supernatural phenomenon around him. But as he notices his sister is frequently comes back home late, he decided to stalk her, only to find out she is doing her duties exorcising evil Youkai alongside her friends Touma and Akinori, and running a Yo-Kai detective agency. With their secret revealed to him, Natsume decided to let him tag along in her activities as they investigate Youkai crimes and take on evil Youkai to maintain peace all over the city. (Source: Wiki)