In the kingdom of Girtonia, the Adenauer family has been giving birth to saints for centuries. Two sisters form the newest generation of holy women who protect the lands from monsters and calamities. The eldest, Philia, is considered a prodigy in the field, capable of solving any problem in no time. Meanwhile, the youngest, Mia, is not as extraordinary as her older sister but has charmed the entire country with her lovely personality. Despite their striking differences, Philia and Mia share an unbreakable bond. Sadly, Mia is the only person who truly cares for Philia. Because of Philia's expressionless face and aloof demeanor, their parents always scold her, and the citizens complain about her. Moreover, Julius Girtonia, the second prince and Philia's fiancé, would rather have a more amicable girl as his wife-to-be. For that reason, he cancels the engagement and sells Philia off to the neighboring kingdom, Parnacorta, which has recently lost its own saint. Having no say on the matter, Philia immediately goes to serve Parnacorta. As a foreigner, she presumes that she will not be treated much better than in Girtonia. Contrary to her expectations, Philia might have finally found a place with people worth smiling for.

A spin-off chibi anime of .

Life hasn't been kind to Zenos. He was born in the slums, and his dirt-poor background has denied him almost every opportunity. After an encounter with a healer, he throws himself into studying to become one and finally catches a break when an adventurer invites Zenos into his party. Zenos is thrilled—so thrilled, in fact, that he's willing to put up with his teammates treating him like garbage. They fail to appreciate his talents and ultimately kick him to the curb, claiming he's outlived his usefulness to them. Now bereft of money and out of options, Zenos decides to put his self-taught skills to use elsewhere and opens an underground clinic. Word quickly spreads about the brilliant healer working incredible magic in the city's shadowy underbelly. Even the royal palace is taking notice... Can Zenos buck the odds and carve out a life for himself in a world that's spit in his face? And can he save the lives of the patients who wind up on his doorstep in the process?

The protagonist genius, Ye Feng, was betrayed and attacked by his senior, and other evildoers, after he refines the Divine Realm pill that would lead him towards Supreme Realm. He managed to fend off and consume the pill, yet finds himself inhabiting the body of his descendant, who bears his name after 500 years later. He pledge to save his current lineage and seeks vengeance, Yefeng embarked on the path of cultivation again, practicing hard and improving while exploring the mystery of the way of heaven.