When Sybel, a freelance reporter, discovers a military plane crash, she is thrilled by the prospect of getting her hands on the latest inside scoop. However, she is unaware that the plane was carrying two top-secret prototype android assassins who will stop at nothing to destroy their target. As the military frantically tries to clean up its mess, Sybel races against time to find and protect the robots' targeted victim—all while documenting the military's misconduct—before it is too late.

Set on the planet Yietta, whose colonists make their living by exploiting the planet's unique liquid-gas oceans, Plastic Little begins as the Yietans are finally about to pay off their debts to the Galactic Federation. Unfortunately, there are those who would rather not let Yietta slip through their fingers... Enter Tita, 17 year old captain of the Cha Cha Maru. Together with her crew, Tita specializes in capturing Yietta's exotic life forms for intergalactic pet shops, but through plain bad luck she finds herself, instead, at the core of a sinister plot to take over Yietta! By rescuing 16 year old Elysse from the very clutches of the military, Tita puts the lives of both herself and her crew in mortal peril... but a girl's got to do what a girl's got to do! As the plotters mobilize their forces in a desperate bid to retrieve Elysse, whom they believe possesses a vital computer code, Tita must play a dangerous game of tag with an entire army of professional killers! It's Cat and Mouse on a planetwide scale, with one crucial difference: Mice don't shoot back, but Tita's does!

When the level of Labor accidents begin to escalate around Tokyo Bay, police detectives Kusumi and Hata are assigned to investigate. What they discover leads to a series of government cover-ups, conspiracy concerning a new biological weapon entitled WXIII-Wasted Thirteen and a tragic, personal connection to Hata. The only hope to stop this threat is to cooperate with the military and lead WXIII into a showdown with the Labors of Special Vehicle Division 2.

The year is around the 1920's and the darkness of the demons have arrived. Now, only the people with large amounts of spirit energy can save the Earth. The Flower Division is now going to be sent out destroy the demons for they're our only hope for survival with their new steam-powered machines and unique fighting techniques.