In Tenikai General Hospital's general diagnostic department, patients who are deemed difficult to treat by other doctors are collected here. From mysteries of unknown illness to murders that even the police can't handle. Genius doctor Takao Ameku reveals the shocking truth hidden behind these mysterious "disease."

In a fantasy world where "jobs" are god-given from birth, heroes are born, not made—and Ein's job of "Appraiser" has put him about as far from the "hero" pedestal as possible. Used, abused, and eventually abandoned by his fellow adventurers, Ein decides it just isn't worth going on. Lucky for Ein, though, the end may just be the beginning, as well as a new lease on life. Turns out, his "worthless" job may just be the key to becoming a hero after all.

What's a guy to do when his life suddenly changes while innocently enjoying a nice, cold drink after work? And I mean really changes. This middle-aged commoner now finds himself in the body of Liam Hamilton, the young son of a noble house teetering on the brink of collapse. Between his fervidly desperate father and his utterly apathetic brothers, the only bright side to his new situation is that Liam can finally try learning magic like he's always wanted. Little does he know his hobby of choice may be about to turn his life upside-down yet again! Will Liam be able to master the craft of magic? And will it be enough to save him from the shadow looming over his family...?

Yuke, a red mage, angrily declares that he's leaving Thunder Pike, the A-rank party he's been with for five years, because he's fed up with being insulted and ridiculed by the other members. While searching for a new party, he runs into his former students Marina, Silk, and Rain, and decides to join their party, Clover. Encouraged by their admiration of him as their teacher, Yuke leads them in completing several quests that show off his own extraordinary magic and skills while bringing out the girls' abilities to their fullest. Then, through an "adventure broadcast" by an artifact known as Camelot, Clover becomes well-known throughout society. The party's dream is to conquer Achromatic Darkness, the most challenging dungeon of all, but as they take on other dungeons in hopes of eventually achieving that goal, they gradually become entangled in chaos that threatens the whole world...