Keitaro Urashima promised a girl when he was young that they would meet up again at Tokyo University in the future. Sadly, in the National Practice Exam, Keitaro ranked 27th from the bottom. Knowing his grandmother owned a hotel, Keitaro intended to stay there while continuing his studies for Tokyo U, only to find out the hotel had long been transformed into an all-girls dormitory. Through an odd twist of fate, Keitaro eventually became the manager of the dorm, beginning his life of living with five other girls.

It all started in Kaminoyama High School, when five best friends—Aoi Miyamori, Ema Yasuhara, Midori Imai, Shizuka Sakaki, and Misa Toudou—discovered their collective love for all things anime and formed the animation club. After making their first amateur anime together and showcasing it at the culture festival, the group vow to pursue careers in the industry, aiming to one day work together and create their own mainstream show. Two and a half years later, Aoi and Ema have managed to land jobs at the illustrious Musashino Animation production company. The others, however, are finding it difficult to get their dream jobs. Shizuka is feeling the weight of not being recognized as a capable voice actor, Misa has a secure yet unsatisfying career designing 3D models for a car company, and Midori is a university student intent on pursuing her dream as a story writer. These five girls will learn that the path to success is one with many diversions, but dreams can still be achieved through perseverance and a touch of eccentric creativity. [Written by MAL Rewrite]

The story takes place shortly before Cartaphilus took a nap and Chise became an auditor at the academy. Elias and his friends help Chise prepare for the academy, where in the middle of everyday life, Spriggan visits the mansion on a spooky horse with the words, "The appearance of the ghost hunting association is unusual this time." Gabriel, an ordinary boy who just moved from London, was bored of his environment of parting with friends, being in an unfamiliar location, and everything else. Sitting by the window and glancing beyond, he spotted a purple smoke and decided to chase after it, looking to escape his boredom. Though it should not, the world of the boy begins to converge with the wizards, who live on the other side behind a thick veil.

Small for his age, Yukinari has been bullied and abused by girls all his life. Now in high school, he has developed a rare condition: whenever girls touch him, or even come close, he breaks out in hives. Imagine his surprise, when he is suddenly transported to the city of Seiren on a mystic world invisibly orbiting the Earth, and populated with vast numbers of women and very few men. Fortunately, he has a new friend, Miharu-chan, whose touch inexplicably doesn't affect him. (Source: ANN)