In the newly formed Shiniki district of Tokyo, Zen Seizaki is a diligent public prosecutor at the Tokyo District Public Prosecutors Office. Assigned to a case involving false advertisement, Zen—along with his assistant officer, Atsuhiko Fumio—investigate Japan Supiri, a pharmaceutical company that had provided fabricated clinical research on the company's new drug. While investigating the file of Shin Inaba, an anesthesiologist connected to the crime, the case takes a dark turn when Zen finds a page stained with a mixture of blood, hair and skin, along with the letter "F" scribbled all across the sheet. As he investigates further, the case goes beyond Zen's imagination and becomes vastly complex, challenging his sense of justice and his knowledge of the truth. Digging deeper into the investigation, Zen begins to uncover a concealed plot behind the ongoing mayoral election and ties to many people of interest involved in the election and those closer than he thinks. The case grows more severe and propels Zen into an unforeseen hurricane of corruption and deceit behind the election, the establishment of the Shiniki district, and the mysterious woman associated with it all. [Written by MAL Rewrite]

After defeating a mysterious enemy, Yuuma Tsukumo, along with the help of Kaito Tenjou and Ryouga "Shark" Kamishiro, has thwarted the Barians' plans. However, Yuuma is still on a quest to retrieve the Number Cards to restore Astral's memories. The Seven Barian Emperors catch wind of Yuuma and Astral's endeavors and begin to collect the cards themselves to achieve their ultimate goal: destroying Astral's world in exchange for saving their own. Though only five of the emperors are present, they unanimously decide on annihilating Astral and Yuuma once and for all. Elsewhere, with their newfound powers of ZEXAL, Astral and Yuuma work to eliminate the enemy force that threatens Earth and the rest of the universe. Yu☆Gi☆Oh! Zexal Second unveils the mysteries and unpleasant surprises that lie in the wake of Yuuma's adversities. As Astral struggles to accept his past and the consequences it may have brought, will the gods continue to shower their fortune upon Yuuma on yet another perilous adventure?

Charley, a cyborg vampire who does the Vatican's dirty work, is the thrall of the local vampire playboy Johnny Rayflo. As the two fight crime—and each other—hilarity, violence and sacrilege ensue! But can Charley resist his own desperate cravings for blood? Find out as the devilish duo go up against a childlike vampire princess, a mysterious branch of the Unitarian Church...and one another.