The main character, a cat named Nyatto, embarks upon a journey to save his sister's soul, which was ripped in two when Nyatto tried to save her from Death. She trails after him, brain-dead. They encounter many brilliant, mind-bending situations, beginning with a disturbing magic show.

Immortality is something many people would wish for. But would it be such a coveted ability if people knew they would be subject to countless attacks because of it? Such is the case for Rin Asougi, an immortal private investigator, because there is no shortage of people who want her dead. Over the centuries, she has met many grisly ends, but each time, she returns to life as if nothing had happened. In 1990, while looking for a lost cat, Rin runs into Kouki Maeno, a man who feels that his memories are wrong. Agreeing to help him, Rin discovers that Kouki is not what he seems, all the while drawing closer to her true enemy. This adversary knows Rin and her kind all too well, and if she dies by his hand, she may stay dead permanently. [Written by MAL Rewrite]

Due to his mother and sister, who both love professional wrestling, Kinjirou Sakamachi developed a resilient body that could take hard punches, aggressive kicks, and even deadly vehicle bumps, in order to survive their various grappling positions and locks. However, he also developed gynophobia, an abnormal fear of women. With just one touch from a girl, his nose bleeds uncontrollably, he sweats excessively, and in rare cases, faints abruptly. His life changes for the worse because of a fated meeting in the restroom. While trying to escape from a girl, he discovers that the most popular student in their school, Subaru Konoe—the butler of the headmaster’s daughter, Kanade Suzutsuki—is actually female! Surprised, Subaru violently assaults Kinjirou, dealing significant damage and knocking him unconscious. When he comes to, he meets Kanade. In exchange for his silence, she promises to help cure his phobia.

Kouichi Sanada and Kazuki Aihara's childhood friend Mao Mizusawa has returned after living in France for a couple of years. Kouichi is surprised to learn that, since her parents are remaining overseas for the time being, his mother has agreed to let Mao stay with them. The three friends help each other deal with the ups and downs of high school romance.