A reunion that was supposed to spell the arrival of peaceful times is quickly shattered when Subaru Natsuki and Emilia return to Irlam village. Witnessing the devastation left behind by the calamities known as Sin Archbishops, Subaru sinks into the depths of despair as his ability to redo proves futile. As the group makes their way to the Sanctuary in search of answers, Subaru has an unexpected encounter with the Witch of Greed—Echidna. Subjected to her untamed rhythm, he is forced to dive into the spirals of the past and future. At the same time, several mysterious threats set their sights on the Sanctuary, heralding a horrific fate for the hapless people trapped within. Everlasting contracts, past sins, and unrequited love will clash and submerge into a river of blood in the second season of Re:Zero kara Hajimeru Isekai Seikatsu. Pushed to the brink of hopelessness, how long will Subaru's resolve to save his loved ones last? [Written by MAL Rewrite]

Takashi Natsume has grown accustomed to his encounters with youkai through the Book of Friends, which contains the names of youkai whom his grandmother, Reiko Natsume, has sealed in contracts. These encounters allow Natsume to better understand the youkai, Reiko, and himself. 

The Book of Friends is a powerful tool that can be used to control youkai; it is sought after by both youkai and exorcists alike. Natsume just wants to live out his daily life in peace but is constantly disrupted by these experiences. If he is to end this torment, Natsume must explore more about the book and the world of exorcism, as well as begin to open his heart to those who can help him.

[Written by MAL Rewrite]

Yabuki Joe is left downhearted and hopeless after a certain tragic event. In attempt to put the past behind him, Joe leaves the gym behind and begins wandering. On his travels he comes across the likes of Wolf Kanagushi and Goromaki Gondo, men who unintentionally fan the dying embers inside him, leading him to putting his wanderings to an end. His return home puts Joe back on the path to boxing, but unknown to himself and his trainer, he now suffers deep-set issues holding him back from fighting. In attempt to quell those issues, Carlos Rivera, a world renowned boxer is invited from Venezuela to help Joe recover.

Takashi Natsume, the timid youkai expert and master of the Book of Friends, continues his journey towards self-understanding and acceptance with the help of friends both new and old. His most important ally is still his gluttonous and sake-loving bodyguard, the arrogant but fiercely protective wolf spirit Madara—or Nyanko-sensei, as Madara is called when in his usual disguise of an unassuming, pudgy cat. Natsume, while briefly separated from Nyanko-sensei, is ambushed and kidnapped by a strange group of masked, monkey-like youkai, who have spirited him away to their forest as they desperately search for the Book of Friends. Realizing that his "servant" has been taken out from right under his nose, Nyanko-sensei enlists the help of Natsume's youkai friends and mounts a rescue operation. However, the forest of the monkey spirits holds many dangerous enemies, including the Matoba Clan, Natsume's old nemesis. Stretching from the formidable hideout of the Matoba to Natsume's own childhood home, Natsume Yuujinchou Shi is a sweeping but familiar return to a world of danger and friendship, where Natsume will finally confront the demons of his own past.