Human beings can be divided into two kinds: ordinary people who work for the living, and the undead who work for the dead. For the undead, their lives are dedicated to fulfilling the final wishes of ghosts who died with regrets. As for Baili Dengfeng, he has one and only one destiny in this world: to find his long-missing wife Ruyan. During his quest, Dengfeng makes acquaintance with Jia Xuan, whose family was murdered and is yet to be avenged, Liang You who is cute, naughty and adores him very much, and Liang Yuan, who simply doubts everything neurotically. After a series of events, he also learns of the existence of Spirit Masters and Spirit Slaves, and gets in touch with a mystical organization named "Spirits Expelling Order". With more and more mysteries being unveiled, the truth is drawing closer and closer to Dengfeng, who perhaps would rather not face the whole of it.

Legends tell the story of Sacred Guardians called Shalen who tried to protect the lands from 4 beasts from another world by using the power of fire, metal, water, wood and earth. However, the beasts were too powerful even for them until a new power was found - the wind spell. The spirits of the beasts were sealed and peace was restored in the human world. Ever-since, people born with a special mark on their hand become Shalen who should protect everyone in the human world. Lang Ming is a young blind boy who has an exceptional hearing. While he lives with his mother in Xiaoyanggang and tries to make money, his town is attacked by a demon and his mother disappears. Lang is ready to do everything in order to find her so he makes a deal with a strange girl, he later calls Little Goblin. This marks the beginning of an epic adventure which will change Lang Ming's life forever.

Yumi Ikoma and Ryou Masaoka are children who have been selected to take part in a top secret mission, to be the pilots of the first Fafner combat units; the last chance of survival for the human race. The enemy is ruthless, remorseless and is able to read the minds of humans. Therefore, the details of this mission are kept a secret even from the personnel involved. The young pilots must use all their courage and faith in order to survive and complete their mission or the fate of mankind would be compromised.

Miura Kyoji, a dedicated kendo student, discovers that his shisho (master) Tate Masanari is a reincarnated Incan warrior named Yawaru who wishes to destroy the world to purify it. Kyoji himself is the warrior Bilka, who foiled Yawaru's plans in their previous lives. Yawaru gathers other awakened spirits to release the powers of nature. Now Kyoji must wrestle with his own fate and decide if he is merely a vessel for the reincarnated soul or if he is truly Miura Kyoji and which will be better able to save the world and the future as he knows it.