Tricked into assassinating his own prospective father-in-law, righteous samurai Raizou Kurima is overwhelmed with guilt. In order to reclaim his honor, Raizou swears vengeance on the lord who gave him those misleading orders. In his pursuit, he is aided by self-proclaimed merchant-of-all-trades Yuuen Usui, who is actually one of the Revengers—assassins who seek justice for the wronged and dispense bloody revenge on their behalf. Tragedy seems destined to follow Raizou as he becomes increasingly intertwined with members of the Revengers. As he begins working as a vigilante alongside them, the complicated web between the corrupt Japanese political elite, the unscrupulous Europeans, and the Revengers gradually reveals itself. The more entangled he becomes in these affairs, the more Raizou realizes that justice is as deceptive as the honor that he sought to redeem.

After dying of overwork in Japan, Dahlia is reborn into a world filled with magic. Raised by a master of magical toolmaking, she develops a passion for the craft and becomes engaged to her father's apprentice. Before her father can see her wed, however, he suddenly passes away. As if this weren't enough, on the day before their wedding, her fiancé announces that he's in love—but not with her! Dahlia finally realizes she needs to live for herself. She vows to be her own woman from now on and devote herself to her craft, even if it's not quite the quiet life she was hoping for! From a chance encounter with a knight to starting her own company, there are challenges aplenty on the horizon. But this young craftswoman is no longer a shrinking violet—she's Dahlia, and she's ready to bloom.

Humans have designed countless worlds—each one born from the unique imagination of its creator. Souta Mizushino is a high school student who aspires to be such a creator by writing and illustrating his own light novel. One day, while watching anime for inspiration, he is briefly transported into a fierce fight scene. When he returns to the real world, he realizes something is amiss: the anime's headstrong heroine, Selesia Yupitilia, has somehow returned with him. Before long, other fictional characters appear in the world, carrying the hopes and scars of their home. A princely knight, a magical girl, a ruthless brawler, and many others now crowd the streets of Japan. However, the most mysterious one is a woman in full military regalia, dubbed "Gunpuku no Himegimi," who knows far more than she should about the creators' world. Despite this, no one knows her true name or the world she is from. Meanwhile, Souta and Selesia work together with Meteora Österreich, a calm and composed librarian NPC, to uncover the meaning behind these unnatural events. With powerful forces at play, the once clear line between reality and imagination continues to blur, leading to a fateful meeting between creators and those they created. [Written by MAL Rewrite]

As with both the Advanced Generation and Diamond & Pearl series before it, the Best Wishes! series begins with only Satoshi, headed off to the Isshu region, located far away from Kanto, Johto, Houen, and Sinnoh, with his Pikachu. After he meets up with the new trainer and rival Shooty and the region's Professor Araragi, he gains traveling companions in Iris, a girl from a town known for its Dragon Pokémon, and Dent, Pokémon Connoisseur and the Grass Pokémon specialist of the three Sanyou City Gym Leaders.