In 356 BC, Alexander the Great arrives in Greece with the ominous destiny that he will become the "destroyer of the world." Inheriting the crown, he becomes king of the Macedonians and starts down a road of conquest with terrific speed. Alexander ultimately confronts his fated nemesis, Darius the Third, in a war with Persia which changes Alexander into the devil he was fated to become, assuring the destruction of all in his path, and possibly himself.

A new tournament, Squad Jam 3, has been announced in the popular VR game Gun Gale Online. This time, Pitohui, one of the best performers in the previous competition, offers to team up with Karen Kohiruimaki, better known in-game as LLENN, the "Pink Devil." Despite her initial reluctance, Karen agrees to join Pitohui's team, LPFM, since she looks forward to facing SHINC, her rivals from the previous Squad Jam. The newly formed LPFM enrolls in the tournament and is quickly recognized as the favorite to win due to the caliber of its players. As they strive to come out on top and win Squad Jam 3, LLENN, Pitohui, and the other members of LPFM battle against other competitors and tackle unexpected challenges.

Falulu is far away in the heart of the PriPara world in Puransu. The sparkle is disappearing from the idol sacred ground PriPara, and Falulu sends an SOS message to Laala and her friends. If the sparkle doesn't return, the PriPara world itself will disappear. Laala and her friends try to help Falulu, and they work together to save the PriPara world.