In her first life, the renowned and genius surgeon Dr. Aoi Takamoto was Elise de Clorance, a villainess of noble descent. Elise's selfishness, insolence, and obsessive love for her fiancé—Prince Linden de Romanoff—led to the deaths of her family members and, eventually, herself. Only after being reborn did Elise realize the error of her ways and decide that, instead of ruining lives, she would devote herself to saving them. But a tragic airplane crash robs her of her dreams too soon. By a miracle, Elise wakes up in her original body before her official engagement to Linden. Recognizing the chance to cherish her loving family and free Linden from an unwanted marriage, Elise wishes to use her advanced medical knowledge to continue down the path of saving lives. In a deal with the emperor, Elise is given only six months to prove that her true place is not on the throne, but rather with the wounded and ailing who desperately need her help.

Expert gamer Tomozaki Fumiya doesn’t exactly fit in, but he wishes he did. With no written rules for success and gameplay that doesn’t work in his favor, the real world seems impossible for someone like him. But, like any noob, all he really needs are some strategies and a seasoned player like Aoi Hinami to help him. Hopefully with her guidance, Tomozaki will gain the experience he needs.

The year is 2222. It has been years since Tears of the New Moon, a mysterious rain, poured and wiped out almost the entire human race. The poisonous rain gave birth to deformed creatures devouring humans, and humanity fled from the danger. As means for survival, the humans then build an underground haven; Amasia. In this newly built dystopian city, in a pursuit of maintaining their existence, they run into an Artificial Intelligence named Magus. Not knowing how things will work between them, the story of how Humans and AI coinciding and trying to find their truths begin.

In a world where the Demon King has died, a host of demigods capable of felling him have inherited the world. A master fencer who can figure out how to take out their opponents with a single glance; a lancer so swift they can break the sound barrier; a wyvern rogue who fights with three legendary weapons at once; an all-powerful wizard who can speak thoughts into being; an angelic assassin who deals instant death. Eager to attain the title of "True Hero," these champions each pursue challenges against formidable foes and spark conflicts among themselves. The battle to determine the mightiest of the mighty begins.