Makino Tsukushi, a girl who comes from a poor family, just wants to get through her two last years at Eitoku Gakuen quietly. But once she makes herself known by standing up for her friend to the F4, the four most popular, powerful, and rich boys at the school, she gets the red card: F4's way of a "Declaration of War." But when she doesn't let herself be beaten by them and is starting to fall for one of the F4, Hanazawa Rui, she starts to see that there is more than meets the eye...

As preparations begin for Seisho Music Academy's yearly Seisho Festival, the girls of the 99th class are gearing up to perform their very own rendition of "Starlight," the tragic tale of two goddesses drawn together by the glow of the heavens but destined to be pulled apart, never to meet again. Created to foster the next generation of theatrical talent, this girls’ only school works to improve the singing, acting, and dancing skills of its students. One student is 16-year-old Karen Aijou, an easygoing girl who has dreamed of performing on stage since she was a child. Her love for theater is further invigorated when her childhood friend Hikari Kagura transfers to Seisho Academy. Through her old friend, Karen stumbles upon a secret elevator leading to a massive theater underneath the school. Hosted by a talking giraffe, this arena serves as a battleground where her classmates participate in duels to determine who among them deserves the title of "Top Star," earning them the right to play one of the lead roles in "Starlight." Emboldened by the promise she made with Hikari to someday be stars together, Karen enters these mysterious battles in the hopes of making their dream a reality.

Taba and the Girls of Kagura Total Security Inc. specialize in jobs where their enemy are "Phantom Cats". They have a few run ins with the various Government agencies, as well as a gang of Phantom Cats; blowing up a lot of stuff along the way. When one of their own is kidnapped, they have to get her back.

Panty and Stocking Anarchy, the angel twin sisters, have even more ghosts to exorcize in Daten City, thanks to the failed opening of the Hell Gate. They must continue their ghost hunt alongside their longtime rivals, the sisters Scanty and Kneesocks Demon, who must earn Hell Coins to return to Hell. On top of that, the Demon sisters are staying at the church with Garterbelt, the priest in charge of the Anarchy sisters. These two polar opposite duos will have to set aside their differences if they wish to collect enough Heaven and Hell Coins to complete their mission and return to their respective realms.